Cheng, J.; Yin, C.H.; Teply, B.A.; Ho, D.; Farokhzad, O.C.; Langer, R.S. "Magnetite-PLGA Microparticles for Oral Delivery of Insulin", Mater. Res. Soc. Symp. Proc., 2005, 873, 581-586.
Xu, X.; Wang, L.; Bi, X.; Cao, T.; Gao, M.; Hu, B.; Zhong, J.; Ji, C.; Sun, R.; Sun, C.; Zhao, Y.; Zhou, Q.; Cheng, J., "Targeted silencing of Engrailed-1 reprograms profibrotic fibroblast lineage for scarless wound healing", Molecular Therapy, 2025, 33, (10), 4889-4903.
Huang, J.; Liu, X.; Yuan, Z.; Yang, T.; Zhao, Y.; Lin, Y.; Song, Z.; Cheng, J., "Facile and Controlled Synthesis of Poly(ethylene glycol)-Polypeptide in an Acidic, Biphasic System", Macromolecules, 2025, 58, (18), 9692-9699.
Sun,C.; Liu,X.; Zhong,J.; Zhou,Q.; Cheng,J. "Reusable Noncomplementary DNA-Based Neural Network", J.Am.Chem.Soc. 2025, 147, (38), 34339-34349.
Lv,H.; Zhang,X.; Zhao,Y.; Cheng,J. "Advances in polypeptide synthesis", Sci.China Chem., 2025.
Cao,T.; Ji,C.; Qin,Q.; Wang,H.; Zhao,Y.; Song,Z.; Cheng,J. "Controlled Synthesis of Telechelic Polypeptides via Polymerization of N-Carboxyanhydrides Mediated by Phosphate Kinetic Modulators", ACS Macro Letters, 2025, 14(6), 858-864.
Gao,M.; Zhong,J.; Liu,X.; Zhao,Y.; Zhu,D.; Shi,X.; Xu,X.; Zhou,Q.; Xuan,W.; Zhang,Y.; Zhou,Y.; Cheng,J. "Deciphering the Role of PEGylation on the Lipid Nanoparticle-Mediated mRNA Delivery to the Liver", ACS Nano, 2025, 19(6), 5966-5978.
Chen, Y.; Xue, T.; Chen, C.; Jang, S.; Braun, P.V.; Cheng, J.; Evans, C.M. "Helical peptide structure improves conductivity and stability of solid electrolytes", Nature Materials, 2024, 23, 1539–1546.
Liu, X.; Huang, J.; Wang, J.; Sheng, H.; Yuan, Z.; Wang, W.; Li, W.; Song, Z.; Cheng, J. "Accelerated and controlled polymerization of N-carboxyanhydrides assisted by acids", CCS Chemistry, 2025, 7, 2769–2780.
Ekatan,S.R.; Xue,T; Song,Z.; Yang,T.; Ndaya,D.; Shaw,M.T.; Cheng,J.; Lin,Y."Thermomechanical Properties of Solid'Liquid Crystalline'Films from Hot-Pressed Synthetic Polypeptides of Various Macromolecular Architectures",Macromolecules,2024,57(5),2008-2018.
Yang,T.; Xue,T.; Mao,J.; Chen,Y.; Tian,H.; Bartolome,A.; Xia,H.; Yao,X.; Kumar,C.V.; Cheng,J.; Lin,Y."Tailoring synthetic polypeptide design for directed fibril superstructure formation and enhanced hydrogel properties",J.Am.Chem.Soc,2024,146(9),5823-5833.
Chen,Y.; Jiang,Y.; Xue,T.; Cheng,J. "Strategies for the eradication of intracellular bacterial pathogens", Biomater. Sci., 2024, 12, 1115-1130.
Ji, G.; Zheng, X.; Hou, X.; Sun, X.; Wang, S.; Li, X.; Cheng, J.; Song, Z. "Modulation of polymerization rate of N-carboxyanhydrides in a biphasic system", CCL, 2024, 35 (1), 108872.
Bo, Y.; Zhou, J.; Cai, K.; Wang, Y.; Feng, Y.; Li, W.; Jiang, Y.; Kuo, S.H.; Roy, J.; Anorma, C.; Gardner, S.H.; Luu, L.M.; Lau, G.W.; Bao, Y.; Chan, J.; Wang, H.; Cheng, J. "Leveraging intracellular ALDH1A1 activity for selective cancer stem-like cell labeling and targeted treatment via in vivo click reaction", Proceedings of the National Academy of Sciences 2023, 120(36), e2302342120.
Wang, W.; Fu, H.; Lin, Y.; Cheng, J.; Song, Z. "Cooperative Covalent Polymerization of N-carboxyanhydrides: from Kinetic Studies to Efficient Synthesis of Polypeptide Materials", Accounts of Materials Research 2023, 4, 604-615.
Yin, Q.; Luo, W.; Mallajosyula, V.; Bo, Y.; Guo, J.; Xie, J.; Sun, M.; Verma, R.; Li, C.; Constantz, C.; Wagar, L.; Li, J.; Sola, E.; Gupta, N.; Wang, C.; Kask, O.; Chen, X.; Yuan, X.; Wu, N.C.; Rao, J.; Chien, Y-H.; Cheng, J.; Pulendran, B.; Davis, M.M. "A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2", Nature Materials 2023, 22, 380-390.
Amaral, I.; Fernandes, H.; Li, J.; Ma, M.; Sriram, G.; Wang, Z.; Yu, B.; Cheng, J.; Southall, M. "Outstanding Reviewers for Biomaterials Science in 2021", Biomaterials Science 2022, 10, 3670-3670.
Fu, H.; Baumgartner, R.; Song, Z.; Chen, C.; Cheng, J.; Lin, Y. "Generalized model of cooperative covalent polymerization: connecting the supramolecular binding interactions with the catalytic behavior", Macromolecules 2022, 6, 2041-2050.
Cheng, J.; Southall, M.E. "Ten years of Biomaterials Science", Biomaterials Science 2022, 10, 6339-6340.
Wang, X.; Zhao, Z.; Xue, T.; Tan, Z.; Song, Z.; Wei, S.; Bo, Y.; Wang, Y.; Cheng, J. "Nanoengineered polypeptides from tetraphenylethylene-functionalized N-carboxyanhydride: Synthesis, self-assembly and intrinsic aggregation-induced emission", Progress in Natural Science: Materials International 2021, 31, 541-545.
Yang, Y.; Ying, H.; Li, Z.; Wang, J.; Ferguson, A.; Zhang, Y.; Cheng, J. "Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent", Nature Communications 2021, 12, 1572.
Jiang, Y.; Chen, Y.; Song, Z.; Tan, Z.; Cheng, J. "Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation", Advanced Drug Delivery Reviews 2021, 170, 261-280.
Xia, Y.; Song, Z.; Tan, Z.; Xue, T. Wei, S.; Zhu, L.; Yang, Y.; Fu, H.; Jiang, Y.; Lin, Y.; Lu, Y.; Ferguson, A.L.; Cheng, J. "Accelerated polymerizaton of N-carboxyanhydrides catalyzed by crown ether", Nature Communications 2021, 12, 372.
Jiang, Y.; Han, M.; Bo, Y.; Feng, Y.; Li, W.; Wu, J.R.; Song, Z.; Zhao, Z.; Tan, Z.; Chen, Y.; Xue, T.; Fu, Z.; Kuo, S.H.; Lau, G.W.; Lujiten, E.; Cheng, J. "'Metaphilic' Cell-Penetrating Polypeptide-Vancomycin Conjugate Efficiently Eradicates Intracellular Bacteria via a Dual Mechanism", ACS central science, 2020, 6, 2267–2276.
Song, Z.; Khaw, Y. M.; Pacheco, L. A.; Tseng, K.-Y.; Tan, Z.; Cai, K.; Ponnusamy, E.; Cheng, J., Inoue, M. "Induction of a higher-ordered architecture in glatiramer acetate improves its biological efficiency in a multiple sclerosis animal model", Biomater. Sci. 2020, 8, 5271.
Song, Z.; Chen, X.; Wang, Z.; King, S.; Yan, H.; Cai, K.; Cheng, J. "Potential bleach activators with improved imide hydrolytic stability", International Journal of Industrial Chemistry, 2020, 11, 177-185.
Wang, S.; Yang, Y.; Ying, H.; Jing, X.; Wang, B.; Zhang, Y.; Cheng, J. "Recyclable, Self-Healable, and Highly Malleable Poly(urethane-urea)s with Improved Thermal and Mechanical Performances", ACS Appl. Mater. Interfaces, 2020, 12, 35403-35414.
Xue, T.; Song, Z.; Wang, Y.; Zhu, B.; Zhao, Z.; Tan, Z.; Wang, X.; Xia, Y.; Cheng, J. “Streamlined synthesis of PEG-polypeptides directly from amino acids”, Macromolecules, 2020, 53, 6589-6597.
Shen, L.; Cai, K.; Yu, J.; Cheng, J. "Facile Click-Mediated Cell Imaging Strategy of Liposomal Azido Mannosamine Lipids via Metabolic or Nonmetabolic Glycoengineering", ACS Omega, 2020, 5, 14111-14115.
Lv, S.; Kim, H.; Feng, L.; Song, Z.; Yang, Y.; Baumgartner, R.; Tseng, K.-Y.; Dillon, S.; Leal, C.; Yin, L.; Cheng, J. "Unimolecular Polypeptide Micelles via Ultra-fast Polymerization of N-Carboxyanhydrides", J. Am. Chem. Soc. 2020, 142, 8570-8574.
Bo, Y.; Jiang, Y.; Chen, K.; Cai, K.; Li, W.; Roy, J.; Bao, Y.; Cheng, J. "Targeting Infected Host Cells in vivo via Responsive Azido-Sugar Mediated Metabolic Cell Labeling Followed by Click Reaction", Biomaterials, 2020, 238, 119843.
Song, Z.; Tan, Z.; Zheng, X.; Fu, Z.; Ponnusamy, E.; Cheng, J. "Manipulating the helix-coil transition profile of synthetic polypeptides through leveraging side-chain molecular interactions", Polym. Chem., 2020, 11, 1445-1449.
Song, Z.; Fu, H.; Baumgartner, R.; Zhu, L.; Shih, K.-C.; Xia, Y.; Zheng, X.; Yin, L.; Chipot, C.; Lin, Y.; Cheng, J."Enzyme-mimetic self-catalyzed polymerization of polypeptide helices", Nature Communications, 2019, 10, 5470.
Song, Z.; Fu, H.; Wang, J.; Hui, J.; Xue, T.; Pacheco, L.A.; Yan, H.; Baumgartner, R.; Wang, Z.; Xia, Y.; Wang, X.; Yin, L.; Chen. C.; Roderiguez-Lopez. J.; Ferguson. A.; Lin. Y.; Cheng. J.“Synthesis of polypeptides via bioinspired polymerization of in situ purified N-carboxyanhydrides”, PNAS, 2019, 116, 10658-10663.
Chen, C.; Fu, H.; Baumgartner, R.; Song, Z.; Lin, Y.; Cheng, J. "Proximity-Induced Cooperative Polymerization in 'Hinged' Helical Polypeptides", J. Am. Chem. Soc., 2019, 141, 8680-8693.
Wang, X.; Song, Z.; Tan, Z.; Zhu, L.; Xue, T.; Lv, S.; Fu, Z.; Zheng, X.; Ren, J.; Cheng, J. “Facile Synthesis of Helical Multiblock Copolypeptides: Minimal Side Reactions with Accelerated Polymerization of N Carboxyanhydrides” ACS Macro Lett.; 2019, 8, 1517−1521.
Chen, X.; Zheng, G.; Cheng, J.; Yang, Y. "Supramolecular Nanotheranostics", Theranostics, 2019, 9, 3014-3016.
Ying, H.; Yang, Y.; Cai, K.; Cheng, J. "Hindered Urea Bond: A Bilaterally Responsive Chemistry to Hydrogen Peroxide", European Journal of Organic Chemistry, 2019, 4, 728-731.
Wang, H.; Liu, Y.; Xu, M.; Cheng, J."Azido-Galactose Outperforms Azido-Mannose for Metabolic Labeling and Targeting of Hepatocellular Carcinoma", Biomater. Sci., 2019, 7, 4166-4173.
Shen, L.; Cai, K.; Yu, J.; Cheng, J. "Novel Liposomal Azido Mannosamine Lipids on Metabolic Cell Labelling and Imaging via Cu-free Click Chemistry",Bioconjugate Chem, 2019, 30, 9, 2317-2322.
Wang, H.; Bo, Y.; Liu, Y.; Xu. M.; Cai. K.; Wang. R.; Cheng, J.; "In Vivo Cancer Targeting via Glycopolyester Nanoparticle Mediated Metabolic Cell Labeling Followed by Click Reaction",Biomaterials, 2019, 119305.
Song, Z.; Tan, Z.; Cheng, J.; "Recent Advances and Future Perspectives of Synthetic Polypeptides from N Carboxyanhydrides", Macromolecules, 2019, 52, 8521-8539.
Jia, Y.; Ying, H.; Zhang, Y.; He, H.; Cheng, J. "Reconfigurable Poly (urea-urethane) Thermoset Based on Hindered Urea Bonds with Triple-shape Memory Performance", Macromol. Chem. Phys., 2019, 1900148.
Mei, Y.; Wang, R.; Jiang, W.; Bo, Y.; Zhang, T.; Yu, J.; Cheng, M.; Wu, Y.; Cheng, J.; Ma, W.;"Recent progress in nanomaterials for nucleic acid delivery in cancer immunotherapy", Biomater. Sci., 2019, 7, 2640-2651.
Wang, H.; Song, Z.; Lao, Y.; Xu, X.; Gong, J.; Cheng, D.; Chakraborty, S.; Park, J.S.; Li, M.; Huang, D.; Yin, L.; Cheng, J.; Leong, K.W. "Nonviral Gene Editing via CRISPR/Cas9 Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide", PNAS, 2018, 115, 4903-4908.
Song, Z.; Fu, H.; Wang, R.; Pacheco, L.A.; Wang, X.; Lin, Y.; Cheng, J. "Secondary structures in synthetic polypeptides from N-carboxyanhydrides: design, modulation, association, and material applications", Chem. Soc. Rev., 2018, 47, 7401-7425.
Lv, S.; Wu, Y.; Cai, K.; He, H.; Li, Y.; Lan, M.; Chen, x.; Cheng, J.; Yin, L. "High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor-Receptor Coordination Interactions", J. Am. Chem. Soc., 2018, 140, 1235–1238.
Zhang, Y.; Cai, K.; Li, C.; Guo, Q.; Chen, Q.; He, X.; Liu, L.; Zhang, Y.; Lu, Y.; Chen, X.; Sun, T.; Huang, Y.; Cheng, J.; Jiang, C. "Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy", Nano Lett., 2018, 18, 1908–1915.
He, H.; Chen, Y.; Li, Y.; Song, Z.; Zhong, Y.; Zhu, R.; Cheng, J.; Yin, L. "Effective and Selective Anti-Cancer Protein Delivery via All-Function-in-One Nanocarriers Coupled with Visible Light-Responsive, Reversible Protein Engineering", Adv. Funct. Mater., 2018, 28(14), 1706710.
He, X.; Zhang, J.; Li, C.; Zhang, Y.; Lu, Y.; Zhang, Y.; Liu, L.; Ruan, C.; Chen, Q.; Chen, X.; Guo, X.; Sun, T.; Cheng, J.; Jiang, C. "Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy", Theranostics, 2018, 8, 4884.
He, X.; Cai, K.; Zhang, Y.; Lu, Y.; Guo, Q.; Zhang, Y.; Liu, L.; Ruan, C.; Chen, Q.; Chen, X.; Li, C.; Sun, T.; Cheng, J.; Jiang, C. "Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy", ACS applied materials & interfaces, 2018, 10, 39455-39467.
Ying, H.; Yang, Y.; Cai, K.; Cheng, J. "Hindered Urea Bond: A Bilaterally Responsive Chemistry to Hydrogen Peroxide", Eur. J. Org. Chem., 2019, 728-731.
Liu, L.; Wang, R.; Wang, C.; Wang, J.; Chen, L.; Cheng, J. "Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy", Biomater. Sci., 2018,6, 997-1001.
Liu, Y.; Song, Z.; Zheng, N.; Nagasaka, K.; Yin, L.; Cheng, J. "Systemic siRNA delivery to tumors by cell-penetrating α-helical polypeptide-based metastable nanoparticles", Nanoscale, 2018, 10, 15339–15349.
Wan, J.; Sun, L.; Wu, P.; Wang, F.; Guo, J.; Cheng, J.; Wang, C. "Light-triggered release of drug conjugates for an efficient combination of chemotherapy and photodynamic therapy", Biomaterials Science, 2018, 6, 997-1001.
Cai, K.; Ying, H.; Cheng, J. "Dynamic Ureas with Fast and pH-independent Hydrolytic Kinetics", Chem. Eur. J., 2018, 24, 7345 –7348.
Wang, R.; Cai, K.; Wang, H.; Yin, C.; Cheng, J. "A caged metabolic precursor for DT-diaphorase responsive cell labeling", Chem.Comm., 2018, 54, 4878–4881.
Wan, J.; Sun, L.; Wu, P.; Wang, F.; Guo, J.; Cheng, J.; Wang, C. "Synthesis of indocyanine green functionalized comblike poly (aspartic acid) derivatives for enhanced cancer cell ablation by targeting the endoplasmic reticulum", Polymer Chemistry, 2018, 9, 1206-1215.
Yin, Q.; Tang, L.; Cai, K.; Yang, X.; Yin, L.; Zhang, Y.; Dobrucki, L.W.; Helferich, W.G.; Fan, T.M.; Cheng, J. "Albumin as a 'Trojan Horse' for Polymeric Nanoconjugates Transendothelial Transport across Tumor Vasculatures for Improved Cancer Targeting", Biomater. Sci., 2018, 6, 1189–1200.
Wang, H.; Wang, R.; Cai, K.; He, H.; Liu, Y.; Yen, J.; Wang, Z.; Xu, M.; Sun, Y.; Zhou, X.; Yin, Q.; Tang, L.; Dobrucka, I.; Dobrucki, L.; Chaney, E.; Boppart, S.; Fan, T.; Lezmi, S.; Chen, X.; Yin, L.; Cheng, J. "Selective In Vivo Cell Labeling Mediated Cancer Targeting", Nature Chemical Biology, 2017, 13, 415-424.
Baumgartner, R., Fu, H.; Song, Z.; Lin, Y.; Cheng, J. "Cooperative polymerization of α-helices induced by macromolecular architecture", Nature Chemistry, 2017, 9, 614–622.
Xiong, M.; Bao, Y.; Xu, X.; Wang, H.; Han, Z.; Wang, Z.; Liu, Y.; Huang, S.; Song, Z; Chen, J.; Peek, R.M. Jr., Yin, L.; Chen, L.; Cheng, J. "Selective Killing of Helicobacter pylori with pH-Responsive Helix-Coil Conformation Transitionable Antimicrobial Polypeptides", PNAS, 2017, 114, 12675-12680.
Song, Z.; Mansbach, R.A.; He, H.; Shik, K.C.; Baumgartner, R.; Zheng, N.; Ba, X.; Huang, Y.; Mani, D.; Nieh, M.P.; Ferguson, A.L.; Yin, L.; Cheng, J. "Modulation of Polypeptide Conformation through Donor-Acceptor Transformation of Side-Chain Hydrogen Bonding Ligands", Nature Commun., 2017, 8, 92.
Song, Z.; Han, Z.; Lv, S.; Chen, C.; Chen, L.; Lin, Y.; Cheng, J. "Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application", Chem. Soc. Rev., 2017, 46, 6570-6599.
Xiong, M.; Han, Z.; Song, Z.; Yu, J.; Ying, H.; Yin, L; Cheng, J. "Bacteria-Assisted Activation of Antimicrobial Polypeptides via Random Coil-to-Helix Transition", Angew. Chem. Int. Ed., 2017, 56, 10826 –10829.
Xia, H.; Fu, H.; Zhang, Y.; Shih, K.; Ren, Y.; Anuganti, M.; Nieh, M; Cheng, J.; Lin, Y. “Supramolecular Assembly of Comb-like Macromolecules Induced by Chemical Reactions that Modulate the Macromolecular Interactions in-situ”, J. Am. Chem. Soc., 2017, 139, 11106-11116.
Chen, J.; Ding, J.; Wang, Y.; Cheng, J.; Ji, S.; Zhuang, X.; Chen, X. "Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors", Advanced Materials, 2017, 29.
Lee, M.W.; Han, M.; Bossa, G.W.; Snell, C.; Song, Z.; Tang, T.; Yin, L.; Cheng, J.; May, S.; Luijten, E.; Wong, GC.L. "Interactions between Membranes and 'Metaphilic' Polypeptide Architectures with Diverse Side-Chain Populations", ACS Nano, 2017, 11, 2858-2871.
Ying, H.; Yen, J.; Wang, R.; Lai, Y.; Hu, Y.; Cheng, J. "Degradable and biocompatible hydrogels bearing a hindered urea bond", Biomater. Sci., 2017, 5, 2398–2402.
Zheng, N.; Song, Z.; Yang, J.; Liu, Y.; Li, F.; Cheng, J.; Yin, L. "Manipulating the membrane penetration mechanism of helical polypeptides via aromatic modification for efficient gene delivery", Acta Biomaterialia., 2017, 58, 146–157.
Ren, Y.; Baumgartner, R.; Fu, H.; Schoot, P.V.D.; Cheng, J.; Lin, Y. "Revisiting the Helical Cooperativity of Synthetic Polypeptides in Solution", Biomacromolecules, 2017, 18, 2324-2332.
Bao, Y.; Wu, X.; Chen, J.; Hu, X.; Zeng, F.; Cheng, J.; Jin, H. Lin, X.; Chen, L. "Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα", PNAS, 2017, 114, 3993-4001.
Baumgartner, R.; Kuai, D.; Cheng, J. "Synthesis of controlled, high-molecular weight poly(L-glutamic acid) brush polymers", Biomater. Sci., 2017, 5, 1836–1844.
Ren, Y.; Fu, H.; Baumgartner, R.; Zhang, Y.; Cheng, J.; Lin, Y. "Folding Cooperativity of Synthetic Polypeptides with or without 'Tertiary' Interactions", ACS Macro Letter, 2017, 6, 733-737.
Lv, S.; Tang, Z.; Song, W.; Zhang, D.; Li, m.; Liu, H.; Cheng, J.; Zhong, W.; Chen, X. "Inhibiting Solid Tumor Growth In Vivo by Non-Tumor-Penetrating Nanomedicine", Small, 2017, 13, 1600954.
Zheng, N.; Song, Z.; Liu, Y.; Yin, L.; Cheng, J. "Gene delivery into isolated Arabidopsis thaliana protoplasts and intact leaves using cationic, α-helical polypeptide", Front. Chem. Sci. Eng., 2017, 11, 521–528.
Tian, J.; Rodgers, Z.; Min, Y.; Wan, X.; Qiu, H.; Mi, Y.; Tian, X.; Wagner, K.T.; Caster, J.M.; Qi, Y.; Roche, K.; Zhang, T.; Cheng, J.; Wang, A.Z. "Nanoparticle delivery of chemotherapy combination regimen improves the therapeutic efficacy in mouse models of lung cancer", Nanomedicine: Nanotechnology, Biology, and Medicine, 2017, 13, 1301-1307.
Cai, K.; Wang, A.Z.; Yin, L.; Cheng, J. "Bio-Nano Interface: The Impact of Biological Environment on Nanomaterials and Their Delivery Properties", J. Controlled Release, 2017, 263, 211-222.
Lv, S.; Wu, Y.; Dang, J.; Tang, Z.; Song, Z.; Ma, S.; Wang, X.; Chen, X.; Cheng, J.; Yin, L. "Investigation on the controlled synthesis and post-modification of poly-[(N-2-hydroxyethyl)-aspartamide]-based polymers", Polym. Chem., 2017, 8, 1872-1877.
Song, Z.; Zhang, R.; Lu, H.; Gabrielson, N.P.; Yin, L.; Ponnusamy, E.; Cheng, J. "Synthesis and Biomedical Applications of Polyamino Acids", Materials Matters, 2016, 8, 78-84.
Wang, H.; Gauthier, M.; Kelly, J. R.; Miller, R.J.; Xu, M.; O'Brien, W.D.; Cheng, J. "Targeted Ultrasound Assisted Cancer-Selective Chemical Labeling and Subsequent Cancer Imaging via Click Chemistry", Angew. Chem. Int. Ed., 2016, 55, 5452-5456.
Wang, R.; Zhang, J.; Yin, Q.; Xu, Y.; Cheng, J.; Tong, R. "Controlled Ring-Opening Polymerization of O-Carboxyanhydrides Using β-Diiminate Zinc Catalyst", Angew. Chem. Int. Ed., 2016, 55, 13010-13014.
Yin, Q.; Tang, L.; Cai, K.; Tong, R.; Sternberg, R.; Yang, X.; Dobrucki, L.W.; Borst, L.B.; Kamstock, D.; Song, Z.; Helferich, W.G.; Cheng, J.; Fan, T.M. "Pamidronate Functionalized Nanoconjugates for Targeted Therapy of Focal Skeletal Malignant Osteolysis", PNAS, 2016, 113, 4601-4609.
Zhang, Y.; Ying, H.; Hart, K.R.; Wu, Y.; Hsu, A.J.; Coppola, A.M.; Kim, T.A.; Yang, K.; Sottos, N.R.; White, S.R.; Cheng, J. "Malleable and Recyclable Poly(urea-urethane) Thermoset Bearing Hindered Urea Bonds", Advanced Materials, 2016, 28, 7646-7651.
Baumgartner, R.; Ryba, K.; Song, Z.; Wang, R.; Harris, K.; Katz, J.S.; Cheng, J. "A delayed curing ROMP based thermosetting resin", Polym. Chem., 2016, 7, 5093-5098.
Bai, Y.; Nguyen, L.T.; Song, Z.; Peng, S.; Lee, J.; Zheng, N.; Kapoor, I.; Hagler, L.D.; Cai, K.; Cheng, J.; Chan, H.Y.; Zimmerman, S.C. "Integrating Display and Delivery Functionality with a Cell Penetrating Peptide Mimic as a Scaffold for Intracellular Multivalent Multi-targeting", J. Am. Chem. Soc., 2016, 138, 9498-9507.
He, H.; Zheng, N.; Song, Z.; Kim, K.H.; Yao, C.; Zhang, R.; Zhang, C.; Huang, Y.; Uckun, F.M.; Cheng, J.; Zhang, Y.; Yin, L. "Suppression of Hepatic Inflammation via Systemic siRNA Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide Hybrid Nanoparticles", ACS NANO, 2016, 10, 1859-1870.
Kang, S.; Murphy, R.; Hwang, S.; Lee, S.; Harburg, D.; Krueger, N.; Shin, J.; Gamble, P.; Cheng, H.; Yu, S.; Liu, Z.; McCall, J.; Stephen, M.; Ying, H.; Kim, J.; Park, G.; Webb, R.; Lee, C.; Chung, S.; Wie, D.; Gujar, A.; Cheng, J.; Huang, Y.; Lee, S.; Braun, P.; Ray, W.; Rogers, J.A."Bioresorbable Silicon Electronic Sensors for the Brain", Nature, 2016, 530, 71-76.
Wang, J.; Yuan, L.; Wang, Z.; Rahman, Md.A.; Huang, Y.; Zhu, T.; Wang, R.; Cheng, J.; Wang, C.; Chu, F.; Tang, C. "Photoinduced Metal-Free Atom Transfer Radical Polymerization of Biomass-Based Monomers", Macromolecules, 2016, 49, 7709-7717.
Xing, H.; Xu, W.; Hwang, K.; Wu, P.; Yin, Q.; Li, Z.; Cheng, J.; Lu, Y. "The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin", Chem. Bio. Chem., 2016, 17, 1111-1117.
Song, Z.; Huang, Y.; Prasad, V.; Baumgartner, R.; Zhang, S.; Harris, K.; Katz, J.S.; Cheng, J. "Preparation of Surfactant-Resistant Polymersomes with Ultrathick Membranes through RAFT Dispersion Polymerization", ACS Applied Materials & Interfaces, 2016, 8, 17033-17037.
Azzi, J.; Yin, Q.; Uehara, M.; Ohori, S.; Tang, L.; Cai, K.; Ichimura, T.; McGrath, M.; Maarouf, M.; Kefaloyianni, E.; Loughhead, S.; Petr, J.; Sun, Q.; Kwon, M.; Tullius, M.; Andrian, U.; Cheng, J.; Abdi, R. "Targeted delivery of immunomodulators to lymph nodes", Cell Reports, 2016, 15, 1202-1213.
Wang, H.; Tang, L.; Liu, Y.; Dobrucki, I.T.; Dobrucki, L.W.; Yin, L.; Cheng, J. "In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates", Theranostics, 2016, 6, 1467-1476.
Ying, H.; Cheng, J. "One-step Construction of Aminosquaraine Backbone", Dyes and pigments, 2016, 131, 264-267.
Li, Y.; Bai, Y.; Zheng, N.; Liu, Y.; Vincil, G.A.; Pedretti, B.J.; Cheng, J.; Zimmerman, S. "Crosslinked Dendronized Polyols as a General Approach to Brighter and More Stable Fluorophores", Chem. Commun., 2016, 52, 3781-3784.
Yen, J.; Ying, H.; Wang, H.; Yin, L.; Uckun, F.; Cheng, J. "CD44 Mediated Non-Viral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic Acid Coated Nanoparticles", ACS Biomater. Sci. Eng., 2016, 2, 326-335.
Cheng, J.; Pun, S.H. "Polymeric biomaterials for cancer nanotechnology", Biomater. Sci., 2015, 3, 891-893.
Xiong, M.; Lee, M.W.; Mansbach, R.A.; Song, Z.; Bao, Y.; Jr. Peek, R. M.; Yao, C.; Chen, L.; Ferguson, A.L.; Wong, GC.L.; Cheng, J. "Helical Antimicrobial Polypeptides with Radial Amphiphilicity", PNAS, 2015, 112, 13155-13160.
Torabi, S.F.; Wu, P.; McGhee, C.E.; Chen, L.; Hwang, K.; Zheng, N.; Cheng, J.; Lu, Y. "In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing", PNAS, 2015, 112, 5903-5908.
Cai, K.; He, X.; Song, Z.; Yin, Q.; Zhang, Y.; Uckun, F.M.; Jiang, C.; Cheng, J. "Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency", J. Am. Chem. Soc., 2015, 137, 3458-3461.
Priftis, D.; Leon, L.; Song, Z.; Perry, S.L.; Margossian, K.O.; Tropnikova, A.; Cheng, J.; Tirrell, M. "Self-Assembly of Alpha-Helical Polypeptides Driven by Complex Coacervation", Angew. Chem. Int. Ed., 2015, 54, 11128-11132.
Tang, L.; Yin, Q.; Xu, Y.; Zhou, Q.; Cai, K.; Yen, J.; Dobrucki, L.W.; Cheng, J. "Bioorthogonal Oxime Ligation Mediated in Vivo Cancer Targeting", Chemical Science, 2015, 6, 2182-2186.
Tang, L.; Tong, R.; Coyle, V.J.; Yin, Q.; Pondenis, H.; Borst, L.B.; Cheng, J.; Fan, T.M. "Targeting Tumor Vasculature with Aptamer Functionalized Doxorubicin-Polylactide Nanoconjugates for Enhanced Cancer Therapy", ACS Nano, 2015, 9, 5072-5081.
Yin, Q.; Yin, L.; Wang, H.; Cheng, J. "Synthesis and biomedical applications of functional poly(alpha-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides", Acc. Chem. Res., 2015, 48, 1777-1787.
Wu, X.; He, C.; Wu, Y.; Chen, X.; Cheng, J. "Nanogel-Incorporated Physical and Chemical Hybrid Gels for Highly Effective Chemo-Protein Combination Therapy", Adv. Funct. Mater., 2015, 25, 6744–6755.
Uckun, F.M.; Mitchell, L.G.; Qazi, S.; Myers, D.E.; Ma, H.; Zheng, N.; Song, Z.; Liu, Y.; Cheng, J. "Development of Polypeptide-Based Nanoparticles for Non-Viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL", EBioMedicine, 2015, 2, 649-659.
Uckun, F.M.; Qazi, S.; Cheng, J.; Myers, D.E. "Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-precursor Leukemia and Yield Superior Survival Outcomes in Mice EBioMedicine", EBioMedicine, 2015, 2, 554-562.
Uckun, F.M.; Ma, H.; Cheng, J.; Myers, D.E.; Qazi, S. "CD22deltaE12 as a molecular target for RNAi therapy", British Journal of Haematology, 2015, 169, 401-414.
Wang, H.; Xu, M.; Xiong, M.; Cheng, J. "Reduction-Responsive Dithiomaleimide-Based Nanomedicine with High Drug Loading and FRET-Indicated Drug Release", Chem. Commun., 2015, 51, 4807-4810.
Zhang, Y.; Yin, Q.; Yen, J.; Li, J.; Ying, H.; Wang, H.; Hua, Y.; Chaney, E.; Boppart, S.; Cheng, J. "Non-Invasive, Real-Time Reporting Drug Release In Vitro and In Vivo", Chem.Commun., 2015, 51, 6948-6951.
Song, Z.; Kim, H.; Ba, X.; Baumgartner, R.; Lee, J.; Tang, H.; Leal, C.; Cheng, J. "Polypeptide Vesicles with Densely Packed Multilayer Membranes", Soft Matter, 2015, 11, 4091-4098.
Baumgartner, R.; Song, Z.; Zhang, Y.; Cheng, J. "Functional Polyesters Derived from Alternating Copolymerization of Norbornene Anhydride and Epoxides", Polym. Chem., 2015, 6, 3586-3590.
Andrade, B.; Song, Z.; Li, J.; Zimmerman, S.; Cheng, J.; Moore, J.S.; Harris, K.; Katz, J. "New Frontiers for Encapsulation in the Chemical Industry", ACS Appl. Mater. Interfaces, 2015, 7, 6359−6368.
Wang, H.C.; Zhang, Y.; Possanza, C.; Zimmerman, S.; Cheng, J.; Moore, J.; Harris, K.; Katz, J. "Trigger Chemistries for Better Industrial Formulations", ACS Appl. Mater. Interfaces, 2015, 7, 6369-6382.
Uckun, F.M.; Qazi, S.; Cheng, J. "Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles", Future Oncology, 2015, 11, 1149-1152.
Lee, J.S.; Deng, X.; Han, P.; Cheng, J. "Dual Stimuli-Responsive Poly(beta-amino ester) Nanoparticles for On-Demand Burst Release", Macromol. Biosci., 2015, 15, 1314-1322.
Zheng, N.; Song, Z.; Liu, Y.; Zhang, R.; Zhang, R.; Yao, C.; Uckun, F.M.; Yin, L.; Cheng, J. "Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery", J. Controlled Release, 2015, 205, 231-239.
Cai, K.; Yen, J.; Yin, Q.; Liu, Y.; Song, Z.; Lezmi, S.; Zhang, Y.; Yang, X.; Helferich, W.G.; Cheng, J. "Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics", Biomater. Sci., 2015, 3, 1061-1065.
Ma, L.; Baumgartner, R.; Zhang, Y.; Song, Z.; Cai, K.; Cheng, J. "UV-Responsive Degradable Polymers Derived from 1-(4-Aminophenyl) ethane-1, 2-diol", J. of Polym. Sci., Part A: Polym. Chem., 2015, 53, 1161-1168.
Gauthier, M.; Yin, Q.; Cheng, J.; O'Brien W.D. "Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles", J. Ultrasound Med., 2015, 34, 1363-1372.
Yin, L.; Chen, Y.; Zhang, Z.; Yin, Q.; Zheng, N.; Cheng, J. "Biodegradable Micelles Capable of Mannose-Mediated Targeted Drug Delivery to Cancer Cells", Macromol. Rapid Commun., 2015, 36, 483-489.
Zhang, R.; Song, Z.; Yin, L.; Lu, H.; Gabrielson, N.P.; Cheng, J. "Ionic α-Helical Polypeptides towards Non-Viral Gene Delivery", WIREs Nanomedicine & Nanobiotechnology, 2015, 7, 98-110.
Mahsan, K.; Chaudhury, I.; Cheng, J.; Safari, M.; Sadeghi, R.; Habibi-Rezaei, M.; Kokini, J. "Immobilization of endo-inulinase on non-porous aminofunctionalized silica nanoparticles", Journal of Molecular Catalysis B: Enzymatic, 2014, 104, 48-55.
Qu, Q.; Dong, L.; Louis, K.R.; Li, X.; Yang, H.; Sun, Q.; Crandall, S.R.; Tsang, S.; Zhou, J.; Cox, C.L.; Cheng, J.; Wang, F. "High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1", Nature Communications, 2014, 5, 3449.
Ying, H.; Zhang, Y.; Cheng, J. "Dynamic urea bond for the design of reversible and self-healing polymers", Nature Communications, 2014, 5, 3218.
Tang, L.; Yang, X.; Yin, Q.; Cai, K.; Wang, H.; Chaudhury, I.; Yao, C.; Zhou, Q.; Kwon, M.; Hartman, J.A.; Dobrucki, I.T.; Dobrucki, L.W.; Borst, L.B.; Lezmi, S.; Helferich, W.G.; Ferguson, A.L.; Fan, T.M.; Cheng, J. "Investigating the optimal size of anticancer nanomedicine", PNAS, 2014, 111, 15344-15349.
Ying, H.; Cheng, J. "Hydrolysable Polyureas Bearing Hindered Urea Bonds", J. Am. Chem. Soc., 2014, 136, 16974-16977.
Uckun, F.M.; Qazi, S.; Ma, H.; Yin, L.; Cheng, J. "A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies", EBioMedicine, 2014, 1, 141-155.
Yin, L.; Huang, X.; Xu, H.; Zhang, Y.; Lam, J.; Cheng, J.; Rogers, J.A. "Materials, Designs, and Operational Characteristics for Fully Biodegradable Primary Batteries", Advanced Materials, 2014, 26, 3879-3884.
Yen, J.; Yin, L.; Cheng, J. "Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure", J. Mater. Chem. B., 2014, 2, 8098-8105.
Zhang, Y.; Wang, R.; Hua, Y.; Baumgartner, R.; Cheng, J. "Trigger-Responsive Poly(β-amino ester) Hydrogels", ACS Macro Letters, 2014, 3, 693-697.
Tong, R.; Tang, L.; Ma, L.; Tu, C.; Baumgartner, R.; Cheng, J. "Smart Chemistry in Polymeric Nanomedicines", Chem. Soc. Rev., 2014, 43, 6982-7012.
Myers, D.E.; Yiv, S.; Qazi, S.; Ma, H.; Cely, I.; Shahidzadeh, A.; Arellano, M.; Finestone, E.; Gaynon, P.; Termuhlen, A.; Cheng, J.; Uckun, F. "CD19-antigen Q1 specific nanoscale liposomal formulation of a SYK Q2 P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells", Integr. Biol., 2014, 6, 766-780.
Zheng, C.; Niu, L.; Pan, W.; Zhou, J.; Lv, H.; Cheng, J.; Liang, D. "Long-term kinetics of DNA interacting with polycations", Polymer, 2014, 13, 2464- 2471.
Karimi, M.; Chaudhury, I.; Cheng, J.; Safari, M.; Sadeghi, R.; Habibi-Rezaei, M.; Kokini, J."Immobilization of endo-inulinase on non-porous aminofunctionalized silica nanoparticles", Journal of Molecular Catalysis B: Enzymatic, 2014, 104, 48-55.
Deng, X.; Zheng, N.; Song, Z.; Yin, L.; Cheng, J. "Trigger-responsive, fast-degradable poly(β-amin ester)s for enhanced DNA unpackaging and reduced toxicity", Biomaterials, 2014, 35, 5006-5015.
Song, Z.; Zheng, N.; Ba, X.; Yin, L.; Zhang, R.; Ma, L.; Cheng, J. "Polypeptides with Quaternary Phosphonium Side Chains: Synthesis, Characterization, and Cell-Penetrating Properties", Biomacromolecules, 2014, 15, 1491-1497.
Zhang, R.; Zheng, N.; Song, Z.; Yin, L.; Cheng, J. "The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides", Biomaterials, 2014, 35, 3443-3454.
Uppada, S.B.; Erickson, T.; Wojdyla, L.; Moravec, D.N.; Song, Z.; Cheng, J.; Puri, N. "Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy", International Journal of Nanomedicine, 2014, 9, 43-53.
Lu, H.; Wang, J.; Song, Z.; Yin, L.; Zhang, Y.; Tang, H.; Tu, C.; Lin, Y.; Cheng, J. "Recent Advances in Amino Acid N-Carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-Assembly and Biological Applications", Chem. Commun., 2014, 50, 139-155.
Yin, Q.; Tong, R.; Yin, L.; Fan, T.M.; Cheng, J. "Anticancer Camptothecin-N-Poly(lactic acid) Nanoconjugates with Facile Hydrolysable Linker", Polym. Chem., 2014, 5, 1581-1585.
Zheng, N.; Yin, L.; Song, Z.; Ma, L.; Tang, H.; Gabrielson, N.P.; Lu, H.; Cheng, J. "Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting", Biomaterials, 2014, 35, 1302-1314.
Zhang, Y.; Yin, Q.; Yin, L.; Ma, L.; Tang, L.; Cheng, J. "Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability", Angew. Chem. Int. Ed., 2013, 52, 6435-6439.
Yin, L.; Song, Z.; Qu, Q.; Kim, K.H.; Zheng, N.; Yao, C.; Chaudhury, I.; Tang, H.; Gabrielson, N.P.; Uckun, F.M.; Cheng, J. "Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation", Angew. Chem. Int. Ed., 2013, 52, 5757-5761.
Yin, L.; Tang, H.; Kim, K.; Zheng, N.; Song, Z.; Gabrielson, N.P.; Lu, H.; Cheng, J. "Light‐Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery", Angew. Chem. Int. Ed. Engl., 2013, 52, 9182–9186.
Yin, L.; Tang, H.; Kim, K.; Zheng, N.; Song, Z.; Gabrielson, N.P.; Lu, H.; Cheng, J. "Light‐Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery", Angew. Chem. Int. Ed. Engl., 2013, 52, 9182–9186.
Yin, Q.; Yap, F.Y.; Yin, L.; Ma, L.; Zhou, Q.; Dobrucki, L.W.; Fan, T.M.; Gaba, R.C.; Cheng, J. "Poly(iohexol) Nanoparticles As Contrast Agents for In Vivo X-ray Computed Tomography Imaging", J. Am. Chem. Soc., 2013, 135, 13620-13623.
Wang, J.; Xia, H.; Zhang, Y.; Lu, H.; Kamat, R.; Dobrynin, A.V.; Cheng, J.; Lin, Y. "Nucleation-Controlled Polymerization of Nanoparticles into Supramolecular Structures", J. Am. Chem. Soc., 2013, 135, 11417-11420.
Tang, H.; Yin, L.; Kim, K.H.; Cheng, J. "Helical Poly(arginine) Mimics with Superior Cell-Penetrating and Molecular Transporting Properties", Chem. Sci., 2013, 4, 3839-3844.
Yin, L.; Song, Z.; Kim, K.H.; Zheng, N.; Gabrielson, N.P.; Cheng, J. "Non-Viral Gene Delivery via Membrane-Penetrating, Mannose-Targeting Supramolecular Self-Assembled Nanocomplexes", Adv. Mater., 2013, 25, 3063-3070.
Uckun, F.M.; Qazi, S.; Cely, I.; Sahin, K.; Shahidzadeh, A.; Ozercan, I.; Yin, Q.; Gaynon, P.; Termuhlen, A.; Cheng, J.; Yiv, S. "Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia", Blood, 2013, 121, 4348-4354.
Yin, L.; Song, Z.; Kim, K.; Zheng, N.; Tang, H.; Lu, H.; Gabrielson, N.; Cheng, J. "Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery", Biomaterials, 2013, 34, 2340-2349.
Song, Z.; Zhang, R.; Lu, H.; Gabrielson, NP; Yin, L.; Ponnusamy, E.; Cheng, J. "Synthesis and Biomedical Applications of Polyamino Acids", Materials Matters, 2013, 8, 78-84.
Wang, H.; Tang, L.; Tu, C.; Song, Z.; Yin, Q.; Yin, L.; Zhang, Z.; Cheng, J. "Redox-Responsive, Core-Cross-Linked Micelles Capable of On-Demand, Concurrent Drug Release and Structure Disassembly", Biomacromolecules, 2013, 14, 3706-3712.
Zhang, Y.; Yin, Q.; Lu, H.; Xia, H.; Lin, Y.; Cheng, J. "PEG-Polypeptide Dual Brush Block Copolymers: Synthesis and Application in Nanoparticle Surface PEGylation", ACS Macro Letters, 2013, 2, 809-813.
Xing, H.; Tang, L.; Yang, X.; Hwang, K.; Wang, W.; Yin, Q.; Wong, N.Y.; Dobrucki, L.W.; Yasui, N.; Katzenellenbogen, J.A.; Helferich, W.G.; Cheng, J.; Lu, Y. "Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo", J. of Mater. Chem. B, 2013, 1, 5288-5297.
Tang, L.; Cheng, J. "Nonporous Silica Nanoparticles for Nanomedicine Application", Nano Today, 2013, 8, 290-312.
Yen, J.; Zhang, Y.; Gabrielson, N.P.; Yin, L.; Guan, L.; Chaudhury, I.; Lu, L.; Wang, F.; Cheng, J. "Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cell", Biomater. Sci., 2013, 1, 719-727.
Yin, Q.; Tong, R.; Xu, Y.; Baek, K.; Dobrucki, L.W.; Fan, T.M.; Cheng, J. "Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug-Poly(O-Carboxyanhydride) Nanoconjugates", Biomacromolecules, 2013, 14, 920-929.
Cameron, J.A.; Milner, D.J.; Lee, J.S.; Cheng, J; Fang, N.X.; Jasiuk, I.M. "Employing the biology of successful fracture repair to heal critical size bone defects", Current Topics in Microbiology and Immunology, 2013, 367, 113-132.
Yin, L.; Song, Z.; Kim, H.K.; Zheng, N.; Tang, H.; Lu, H.; Gabrielson, N.P.; Cheng, J. "Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery", Biomaterials, 2013, 34, 2340-2349.
Mirshafiee, V.; Mahmoudi, M.; Lou, K.; Cheng, J.; Kraft, M.L. "Protein Corona Significantly Reduces Active Targeting Yield", Chem.Commun., 2013, 49, 2557-2559.
Tang, L.; Gabrielson, N.P.; Uckun, F.M.; Fan, T.M.; Cheng, J. "Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates", Mol. Pharmaceutics, 2013, 10, 883-892.
Zhang, Z.; Yin, L.; Tu, C.; Song, Z.; Zhang, Y.; Xu, Y.; Tong, R.; Zhou, Q.; Ren, J.; Cheng, J. "Redox-Responsive, Core Cross-Linked Polyester Micelles", ACS Macro Lett., 2013, 2, 40-44.
Zhang, Y.; Ma, L.; Deng, X.; Cheng, J. "Trigger-Responsive Chain-Shattering Polymers", Polym. Chem., 2013, 4, 224-228.
Tang, L.; Yang, X.; Dobrucki, L.W.; Chaudhury, I.; Yin, Q.; Yao, C.; Lezmi, S.; Helferich, W.G.; Fan, T.M.; Cheng, J. "Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugate for targeted dual-modal imaging of lymph nodes with metastatic tumors", Angew. Chem. Int. Ed., 2012, 51, 12721-12726.
Gabrielson, N.P.; Lu, H.; Yin, L.; Li, D.; Wang, F.; Cheng, J. "Reactive and Bioactive Cationic a-Helical Polypeptide Template for Non-Viral Gene Delivery", Angew. Chem. Int. Ed., 2012, 51, 1143-1147.
Tong, R.; Cheng, J. "Zinc complex mediated regioselective O-acylation of therapeutic agents", Chemical Science, 2012, 3, 2234-2239.
Gabrielson, N. P.; Lu, H.; Yin, L.; Kim, K.H.; Cheng, J. "A Cell-Penetrating Helical Polymer for siRNA Delivery to Mammalian Cells", Molecular Therapy, 2012, 20, 1599-1609.
Tong, R.; Gabrielson, N.P.; Fan, T.M.; Cheng, J. "Polymeric Nanomedicine Based on Poly(lactide) and Poly(lactic-co-glycolide)", Current Opinion in Solid State & Materials Science, 2012, 16, 323-332.
Zhang, Z.; Yin, L.; Xu, Y.; Ren, J.; Cheng, J. "Facile Functionalization of Polyesters through Thiol-yne Chemistry for the Design of Degradable, Cell‒Penetrating and Gene Delivery Dual‒Functional Agents", Biomacromolecules, 2012, 13, 3456-3462.
Tang, H.; Yin, L.; Lu, H.; Cheng, J. "Water-Soluble Poly(L-serine)s with Elongated and Charged Side-Chains: Synthesis, Conformations and Cell-Penetrating Properties", Biomacromolecules, 2012, 13, 2609-2615.
Cely, I.; Yiv, S.;Yin, Q.; Shahidzadeh, A.; Tang, L.; Cheng, J.; Uckun, F.M. "Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles", J. Anal. Oncol., 2012, 1, 1-9.
Li, L.; Yin, Q.; Cheng, J.; Lu, Y. "Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells", Adv. Healthcare Mater., 2012, 1, 567-572.
Tang, L.; Azzi, J.; Kwon, M.; Mounayar, M.; Tong, R.; Yin, Q.; Moore, R.; Skartsis, N.; Fan, T.M.; Abdi, R.; Cheng, J. "Immunosuppressive Activity of Size-Controlled PEG-PLGA Nanoparticles Containing Encapsulated Cyclosporine A", Journal of Transplantation, 2012, 896141, 1-9.
Tang, L.; Fan, T.M.; Borst, L.B.; Cheng, J. "Synthesis and Biological Response of Size-Specific, Monodisperse Drug-Silica Nanoconjugates", ACS Nano., 2012, 6, 3954-3966.
Lu, Y.; Yin, L.; Zhang, Y.; Zhang, Z.; Xu, Y.; Tong, R.; Cheng, J. "Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-L-serine Carboxyanhydrides", ACS Macro Letters, 2012, 1, 441-444.
Tong, R.; Cheng, J. "Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates", Macromolecules, 2012, 45, 2225-2232.
Chen, K.; Tang, L.; Garcia, M.A.; Wang, H.; Lu, H.; Lin, W.; Hou, S.; Yin, Q.; Shen, C.K.F.; Cheng, J.; Tseng, H.R. "The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles", Biomaterials, 2012, 33, 1162-1169.
Lu, H.; Wang, J.; Bai, Y.; Lang, J.W.; Liu, S.; Lin, Y.; Cheng, J. "Ionic Polypeptides with Unusual Helical Stability", Nature Communications, 2011, 2, 206.
Mishra, A.; Lai, G.H.; Schmidt, N.W.; Sun, V.Z.; Rodriguez, A.R., Tong, R.; Tang, L.; Cheng, J.; Deming, T.J.; Kamei, D.T.; Wong, G.C.L. "Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions", PNAS, 2011, 108, 16883-16888.
Wang, J.; Lu, H.; Kamat, R.; Pingali, S.V.; Urban, V.S.; Cheng, J.; Lin, Y. "Supramolecular Polymerization from Polypeptide-Grafted Comb Polymers", J. Am. Chem. Soc., 2011, 133, 12906-12909.
Tong, R.; Tang, L.; Yin, Q.; Cheng, J. "Drug-polyester conjugated nanoparticles for cancer drug delivery", IEEE. Eng. Med. Biol. Soc., 2011, 3, 8337-8339.
Wang, J.; Lu, H.; Ren, Y.; Zhang, Y.; Morton, M.; Cheng, J.; Lin, Y. "Interrupted Helical Structure of Grafted Polypeptides in Brush-Like Macromolecules", Macromolecules, 2011, 44, 8699-8708.
Bai, Y.; Lu, H.; Ponnusamy, E.; Cheng, J. "Synthesis of Hybrid Block Copolymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of NCA", Chem. Commun., 2011, 47, 10830-10832.
Zhang, Y.; Lu, H.; Yao, L.; Cheng, J. "Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations", Macromolecules, 2011, 44, 6641-6644.
Lu, H.; Bai, Y.; Wang, J.; Gabrielson, N.; Wang, F.; Lin, Y.; Cheng, J. "Ring-Opening Polymerization of g-(4-Vinylbenzyl)-L-Glutamate N-Carboxyanhydride for the Synthesis of Functional Polypeptides", Macromolecules, 2011, 44, 6237-6240.
Cheng, J.; Deming, T.J. "Synthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides", Top Curr. Chem., 2011, 310, 1-26.
Li, D.; Zhou, J.; Chowdhury, F.; Cheng, J.; Wang, N.; Wang, F. "Role of mechanical factors in fate decisions of stem cells", Regen. Med., 2011, 6, 229-240.
Chan, J.M.; Zhang, L. F.; Tong, R.; Ghosh, D.; Gao, W.; Liao, G.; Yuet, K.; Gray, D.; Rhee, J.W.; Cheng, J.; Golomb, G.; Libby, P; Langer, R.; Farokhzad, O. "Spatiotemporal Controlled Delivery of Nanoparticles to Injured Vasculature", PNAS, 2010, 107, 2213-2218.
Li, C.; Zhang, Y.; Hu, J.; Cheng, J.; Liu, S. "Reversible Three-State Switching of Multicolor Fluorescence Emission via Multiple Stimuli-Modulated FRET Processes within Thermoresponsive Polymeric Micelles", Chem. Int. Ed., 2010, 49, 5120-5124.
Gabrielson, N.; Xu, Y.; Cheng, J. "Multiplexed supramolecular self-assembly for non-viral gene delivery", Biomaterials, 2010, 31, 9117-9127.
Azzi, J.; Tang, L.; Moore, R.; Tong, R.; Haddad, N.El.; Akiyoshi, T.; Mfarrej, B.; Yang, S.; Jurewicz, M.; Ichimura, T.; Lindeman, N.; Cheng, J.; Abdi, R. "Polylactide-Cyclosporin A Nanoparticles for Targeted Immunosuppression", FASEB J., 2010, 24, 3927-3938.
Yang, X.; Shi, C.; Tong, R.; Qian, W.; Zhau, H. E.; Wang, R.; Zhu, G.; Cheng, J.; Yang, Y.; Cheng, T.; Henary, M.; Strekowski, L.; Chung, L.W.K. "Near IR Heptamethine Cyanine Dye–Mediated Cancer Imaging", Clinical Cancer Research, 2010, 16, 2833-2844.
Tong, R.; Coyle, V.J.; Li, T.; Barger, A.M.; Fan, T.M.; Cheng, J. "Polylactide Nanoparticles Containing Stably-Incorporated Cyanine Dyes for In Vitro and In Vivo Imaging Applications", Microscopy Research and Technique, 2010, 73, 901-909.
Chaney, E.J.; Tang, L.; Tong, R.; Cheng, J.; Boppart, S.A. "Lymphatic Biodistribution of Polylactide Nanoparticles", Molecular Imaging, 2010, 9, 153-162.
Tong, R.; Cheng, J. "Controlled Synthesis of Camptothecin-Polylactide Conjugates Nanoconjugates ", Bioconjugate Chem., 2010, 21, 111-121.
Tong, R.; Yala, L.; Fan, T.M.; Cheng, J. "The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells", Biomaterials, 2010, 31, 3043-3053.
Lu, H.; Wang, J.; Lin, Y.; Cheng, J. "One-Pot Synthesis of Brush-Like Polymers via Integrated Ring-Opening Metathesis Polymerization and Polymerization of Amino Acid N-Carboxyanhydrides", J. Am. Chem. Soc., 2009, 131, 13582-13583.
Cao, Z.; Tong, R.; Xu, W.; Wong, G.W.L.; Cheng, J.; Lu, Y. "Reversible cell-specific delivery of chemotherapy drugs using aptamer-functionalized liposomes", Angew. Chem. Int. Ed., 2009, 48, 6494-6498.
Tong, R.; Cheng, J. "Ring-Opening Polymerization Mediated-Controlled Formulation of Polylactide Nanoparticles", J. Am. Chem. Soc., 2009, 131, 4744-4754.
Yigit, M.V.; Mishra, A.; Tong, R.; Cheng, J.; Wong, G.C.L.; Lu, Y. "Inorganic mercury detection and controlled release of chelating agents from ion-responsive PEG-liposomes", Chem. Biol., 2009, 16, 937-942.
Tong, R.; Tang, L.; Yala, L.; Cheng, J. "Controlled formulation of doxorubicin-polylactide nanoconjugates for cancer drug delivery", IEEE. Eng Med Biol Soc. 2009, 1, 2400-2402.
Tong, R.; Christian, D.A.; Tang, L.; Cabral, H.; Baker, J.R. Jr.; Kataoka, K.; Discher, D.; Cheng, J. "Nanopolymeric Therapeutics", MRS Bulletin, 2009, 34, 422-431.
Lu, H.; Cheng, J. "N-Trimethylsilyl Amines for Controlled Ring-Opening Polymerization of Amino Acid N-Carboxyanhydrides and Facile End Group Functionalization of Polypeptides", J. Am. Chem. Soc., 2008, 130, 12562–12563.
Tong, R.; Cheng, J. "Paclitaxel-Initiated, Controlled Polymerization of Lactide for the Formulation of Polymeric Nanoparticulate Delivery Vehicles", Angew. Chem. Int. Ed., 2008, 47, 4830-4834.
Lee, J.S.; Cheng, J.; Kim, K.Y. "Next Generation Nanosolutions for Cancer Treatment and Diagnosis", Cancer and Chemotherapy Review, 2008, 3, 144-151.
Teply, B.A.; Tong, R.; Jeong, S.Y.; Luther, G.; Sherifi, I.; Yim, C.H.; Khademhosseini, A.; Farokhzad, O.C.; Langer, R.; Cheng, J. "The Use of Charge-Coupled Polymeric Microparticles and Micromagnets for Modulation the Bioavailability of Orally Delivered Macromolecules", Biomaterials, 2008, 29, 1216-1223.
Lu, H.; Cheng, J. "Hexamethyldisilazane-Mediated Controlled Polymerization of α-Amino Acid-NCarboxyanhydrides", J. Am. Chem. Soc., 2007, 129, 14114-14115.
Tong, R.; Cheng, J. "Anticancer Polymeric Nanomedicines", Polymer Reviews, 2007, 47, 345-381.
Karp, J.M.; Yeh, J.; Eng, G.; Fukuda, J.; Blumling, J.; Suh, K.Y.; Cheng, J.; Mahdavi, A.; Borenstein, J.; Langer, R.; Khademhosseini, A. "Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells", Lab Chip, 2007, 7, 786-794.
Cheng, J.; Teply, B.; Sherifi, I.; Sung, J.; Luther, G.; Gu, F.X.; Levy-Nissenbaum, E.; Langer, R.S.; Farokhzad, O.C. "Formulation of Functionalized PLGA-PEG Nanoparticles for In Vivo Targeted Drug Delivery", Biomaterials, 2007, 28, 869-876.
Farokhzad, O.C.; Cheng, J.; Teply, B.A.; Sherifi, I.; Jon, S.; Kantoff, P.W.; Richie, J.P.; Langer, R. "Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo", PNAS, 2006, 103, 6315-6320.
Cheng, J.; Zeidan, R.; Mishra, M.; Liu, A.; Pun, S.H.; Kulkarni, R.P.; Jensen, G.S.; Bellocq, N.; Davis, M.E. "Structure-Function Correlation of Chloroquine and Analogues as Transgene Expression Enhancers in Non-Viral Gene Delivery", J. Med. Chem., 2006, 49, 6522-6531.
Schluep, T.; Hwang, J.; Cheng, J.; Heidel, J.D.; Derek, W.; Bartlett, D.W.; Davis, M.E. "Preclinical Efficacy of the Camptothecin-Polymer Conjugate IT-101 in Multiple Cancer Models", Clinical Cancer Research, 2006, 12, 1606-1614.
Cheng, J.; Teply, B.; Yim, C.; Jeong, S.Y.; Sherifi, I.; Jon, S.; Khademhosseini, A.; Farokhzad, O.C.; Langer, R. "Magnetically Responsive Polymeric Microparticles for Oral Delivery of Protein Drugs", Pharmaceutical Research, 2006, 23, 557-564.
Fukuda, J.; Khademhosseini, A.; Yeh, J.; Eng, G.; Cheng, J.; Farokhzad, O.C.; Langer, R. "Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components", Biomaterials, 2006, 27,1479-86.
Schluep, T.; Cheng, J.; Khin, K.T.; Davis, M.E. "Pharmacokinetics and biodistribution of the camptothecin-polymer conjugate IT-101 in rats and tumor bearing mice", Cancer Chemotherapy and Pharmacology, 2006, 57, 654-662.
Address:No. 600 Dunyu Road, Sandun Town, Xihu District 310030 Hangzhou, Zhejiang PR China
Email:chengjianjun@westlake.edu.cn (research affairs)